منابع مشابه
Epithelial adhesive junctions
Epithelial adhesive cell-to-cell contacts contain large, plasma membrane-spanning multiprotein aggregates that perform vital structural and signaling functions. Three prominent adhesive contacts are the tight junction, adherens junction, and the desmosome. Each junction type has unique cellular functions and a complex molecular composition. In this review, we comment on recent and exciting adva...
متن کاملSnapShot: Epithelial Tight Junctions
Tight junctions form a morphological and functional border between the apical and basolateral cell surface domains that serves as a paracellular diffusion barrier, enabling epithelial cells to separate compartments of different composition. Tight junctions also contribute to the generation and maintenance of cell polarity and regulate signaling mechanisms that guide cell behavior, shape, and ge...
متن کاملEpithelial junctions and attachments.
A distinctive feature of polarized epithelial cells is their specialized junctions, which contribute to cell integrity and provide platforms to orchestrate cell shape changes. The chapter discusses the composition and assembly of C. elegans cell-cell and cell-extracellular matrix junctions, proteins that anchor the cytoskeleton and mechanisms involved in establishing epithelial polarity. The fo...
متن کاملEpithelial junctions, cytoskeleton, and polarity.
A distinctive feature of polarized epithelial cells is their specialized junctions, which contribute to cell integrity and provide platforms to orchestrate cell shape changes. This chapter discusses the composition, assembly and remodeling of C. elegans cell-cell (CeAJ) and hemidesmosome-like cell-extracellular matrix junctions (CeHD), proteins that anchor the cytoskeleton, and mechanisms invol...
متن کاملCholera toxin notches epithelial junctions.
Cholera toxin (CT) is the factor responsible for watery diarrhea associated with Vibrio cholerae infection. In this issue, Guichard et al. (2013) report that CT compromises intestinal epithelium barrier function via cyclic AMP (cAMP)-induced disruption of Rab11- and exocyst-dependent delivery of endocytic recycling cargo to cell-cell junctions.
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ژورنال
عنوان ژورنال: F1000Prime Reports
سال: 2014
ISSN: 2051-7599
DOI: 10.12703/p6-1